| abstract |
The present invention provides compounds of Formula (i) wherein Q1, Q2, Q3, Q4, YI, Y2 and Z are as defined in the description and the pharmaceutical salts thereof and C1-C8 alkyl esters thereof, which are useful for the treatment of diseases responsible for the inhibition of the enzyme 15-lipoxygenase. In addition, the compounds of Formula (I) and their pharmaceutically acceptable salts are useful for the treatment of diseases with an inflammatory component including arteriosclerosis, diseases involving monolith chemotaxis, inflammation, stroke, coronary artery disease , asthma, arthritis, colorectal cancer and psoriasis. |