http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MX-PA02010274-A

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a7f82940e47ba7a1188f8e2ffca55e0f
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-79
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D221-16
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-79
filingDate 2001-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_704a653507b54f8d3df34334b886efac
publicationDate 2003-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber MX-PA02010274-A
titleOfInvention SYNTHESIS OF USEFUL INTERMEDIARIES IN THE PREPARATION OF TRICYCLE COMPOUNDS.
abstract A process for preparing a compound having the formula (I) is provided; (See formula I) comprising: (a) the reaction of a compound having formula (II) (See formula II) with an isocyanate having formula R1NCO to produce a compound having formula (III); (See formula III) (b) optionally hydrolyzing the compound of formula (III) to form an amide having the formula (IV); (See formula IV) (c) the reaction of a compound of formula (III) or the amide of formula (IV) with a compound having formula (V) (See formula V) in the presence of a strong base to produce a compound having the formula (VI); (See formula VI) and (d) the location of the compound of formula (VI) to obtain the compound of formula (I) wherein R is H or CI; M is selected from the group consisting of Li, Na, K, MgX, ZnRA, and AI (RA) 2; RA is alkyl; X is halo; R1 is selected from the group consisting of alkyl, aryl, aralkyl, heteroaryl, heteroaralkyl, cycloalkyl, cycloalkylalkyl, heterocycloalkyl, and heterocycloalkylalkyl; and L is a leaving group; A process is also provided for preparing a compound having the formula (VIII) comprising the reaction of a compound having the formula (II) with CO2 and a protonation agent to obtain the fomiula compound (VIII), wherein M it is selected from the group consisting of Li, Na, K, MgX, ZnRA, and AI (RA) 2, where RA is alkyl and X is halo.
priorityDate 2000-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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