abstract |
The present invention relates to a novel human gene encoding a polypeptide that is a member of the cytochrome P450 family. More specifically, the present invention relates to a polynucleotide encoding a novel human polypeptide called cytochrome P450TEC (Thymus Expressed Cytochrome). This invention also relates to P450TEC polypeptides, as well as vectors, host cells and antibodies directed to P4SOTEC polypeptides, and to recombinant methods for producing them. Therapeutic methods for treating disorders related to P450TEC are also provided. The invention also relates to selection methods for identifying agonists and antagonists of the activity of P450TEC. |