| abstract |
Pharmaceutical compositions comprising a macromolecular pharmaceutical agent in mixed micellar form are described. The mixed micelles are formed from an alkali metal alkyl sulfate, and at least three different compounds that form micelles as described in the specification. The size of the micelle varies between approximately 1 and 10 nanometers. The methods for making and using the compositions are also described. A preferred method of administering the present composition is through the mouth region of the mouth. |