| abstract |
The present invention relates to a preparation containing a combination of active substances consisting of a topical antifungal agent, a systemic antifungal agent, and a physiologically safe enamel base. The preparation of the present invention is suitable for the treatment of onychomycosis. The invention preferably uses water insoluble enamel preparations and a combination of at least one systemic antifungal agent selected within. from the group consisting of itraconazole, terbinafine, fluconazole, or salts thereof with at least one antifungal topical agent selected within the group containing cyclopyrox, or- (2,4-trimethylpentyl) -l-hydroxy-4-methyl -2 (1H) -pyridone, amorolfine and butenaphine or salts thereof. |