| abstract |
Methods are provided to treat injury to or disease of the central or peripheral nervous system; In one embodiment, the treatment is performed by administering activated T cells that recognize a Cop 1 antigen or a peptide or polypeptide related to Cop 1 to promote nerve regeneration or to prevent or inhibit neuronal degeneration within the nervous system; in another embodiment, the treatment involves the administration of Cop 1 or a peptide or polypeptide related to Cop 1 to promote nerve regeneration or to prevent or inhibit neuronal degeneration in the nervous system, be it the central nervous system or the peripheral nervous system ; activated T cells, which have been activated by the presence of Cop 1 or a peptide or polypeptide related to Cop 1, can be administered alone or in combination with Cop 1 or a peptide or polypeptide related to Cop 1. |