abstract |
Pharmaceutical compositions are provided comprising one or more dose units that can be delivered orally, each comprising a selective water soluble low cyclooxygenase-2 inhibitor drug, for example, celecoxib, in a fraction of immediate release and a fraction of controlled release, slow release, scheduled release, release over time, pulse release, sustained release or extended release. The compositions are useful in the treatment and / or prophylaxis of conditions or disorders mediated by cyclooxygenase-2. |