http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MX-PA02006132-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_27a71ddaaa2f5a8c228fc6cb3f3b3098 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D237-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C317-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C317-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D237-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D237-08 |
| filingDate | 2000-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_839067aac7482f0136fc0c3da3bce020 |
| publicationDate | 2002-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | MX-PA02006132-A |
| titleOfInvention | PROCEDURE FOR THE PREPARATION OF DERIVATIVES OF PIRAZOLOPIRIDAZINA. |
| abstract | The invention provides a process for preparing a compound of formula (1): (see formula) and pharmaceutically acceptable derivatives thereof in which: R0 is halogen, C1-6 alkyl, C1-6 alkoxy, C1 alkoxy -6 substituted by one or more fluorine atoms, or O (CH2) nNR4R5; R1 and R2 are independently selected from H, C1-6 alkyl, C1-6 alkyl substituted by one or more fluorine atoms, C1-6 alkoxy, C1-6 hydroxyalkyl, SC1-6 alkyl, C (O ) H, C (O) C1-6 alkyl, C1-6 alkylsulfonyl, C1-6 alkoxy substituted by one or more fluorine atoms, O (CH2) nCO2Cl-6 alkyl, O (CH2) nSC1-6 alkyl, (CH2) nNR4R5, (CH2) nSC1-6 alkyl or C (O) NR4R5; with the proviso that when R0 is in position 4 and is halogen, at least one of Rl and R2 is C1-6 alkylsulfonyl, C1-6 alkoxy substituted by one or more fluorine atoms, O (CH2) nCO2Cl- 6 alkyl, O (CH2) nSC1- or alkyl, (CH2) nNR4R 'or (CH2) nSC1- or alkyl, C (O) NR4R5; R3 is C1-6 alkyl or NH2; R4 and R5 are independently selected from H, or C1-6 alkyl, or, together with the nitrogen atom to which they are attached, form a saturated 4-8 membered ring; and n is 1-4; which comprises oxidizing a corresponding compound of formula (11) or an isomer thereof. |
| priorityDate | 1999-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 62.