| abstract |
This invention is directed to a compound of the formula (I) (see formula) that is useful for inhibiting Factor Xa activity, by contacting the compound with a composition containing Factor Xa. The present invention is also directed to compositions containing compounds of the formula (I), to methods for their preparation, use, such as inhibiting thrombin formation or to treat a patient suffering from, or is subject to, a condition. of disease associated with a harmful physiological excess of thrombin. |