abstract |
Tocol-based compositions of amphiphilic-charged compounds and water-soluble pharmaceutically active compounds or of their charged precursors that are prepared by forming a tocol soluble ionic pair with a counter-ionic-forming compound, with opposite charge, capable of forming a soluble ionic pair in tocol with the active compound. New compounds such as tocopherol succinate-aspartate and tocopherol succinate-glutamate are also disclosed, which are useful as ionic pair forming compounds. |