| abstract |
The derivatives of glucopyranosyloxypyrazole, represented by the general formula (1): (see formula) that have the effect of inhibiting the activity of human SGLT2, and are useful as preventives or as remedies for diabetes, the complication of diabetes or obesity; or its pharmacologically acceptable salts. In said formula, R 1 represents hydrogen or lower alkyl; one of Q1 and T1 represents a group of the formula A: (see formula) while the other represents lower alkyl or halogenated lower alkyl, and R2 represents hydrogen, lower alkyl, lower alkoxy, lower alkylthio, halogenated lower alkyl or halogen. |