| abstract |
The present invention relates to compositions, apparatus and methods useful for consecutively carrying out multiple biological or chemical analyzes of high performance, using repeated sample formations. A combination of the present invention comprises a surface, which comprises a plurality of test regions, at least two of which, and in a preferred embodiment, at least 20 of which, are substantially identical, wherein each of the test regions comprises a formation of generic anchor molecules. The anchors are associated with bifunctional connecting molecules, each containing a part that is specific for at least one of the anchors, and a portion that is a specific sample for an objective of interest. The resulting sample formation is used to analyze the presence or to test the activity of one or more target molecules, which interact specifically with the samples. In one embodiment of the invention, the test regions (which may be wells), are further subdivided into smaller subregions (indentations or crevices). |