| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c76ecadad74a1a35270b3e3a34d60f37 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D453-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-439 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P-
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D453-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-435
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4375
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K-
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D-
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-08 |
| filingDate |
2000-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_038818efe6295ac50df7b6b735b87843 |
| publicationDate |
2002-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
MX-PA01012328-A |
| titleOfInvention |
POLYMORPHES OF A CITRATE OF (2-BENZHIDRIL- 1-AZABICICLO (2.2.2) OCT-3-IL- (5-ISO-PROPIL-2- METOXIBENCIL) -AMINE AS ANTAGONISTS OF THE NK-1 RECEIVER. |
| abstract |
Two crystalline polymorphic forms of (2-benzhydryl-1-azo-bicyclo [2.2.2] oct-3-yl) - 5- (5-isorpopil-2-methoxy benzyl) amine monohydrate citrate (monohydrates) are the form A and form B; The pharmaceutical composition containing at least one of these polymorphs has an advantageous stability for the formulation for the treatment of acute emesis in patients receiving chemotherapy, the administration of this pharmaceutical composition is conventionally oral, preferably with tablets or capsules, and intravenous; a method of obtaining forms A and B is also described. |
| priorityDate |
1999-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |