| abstract |
The invention relates to the new products of the formula (I), wherein: Z represents -CH2-, -SO2-, -CO-, COO-, -CONH- or - (CH2) 2-NR3-; n represents 0 or 1; R1 represents hydrogen, aryl, -CH-aryl, -SO2-aryl, -CO-aryl, heterocyclic, -CH2-heterocyclic, alkyl and -SO2-alkyl; R2 represents alkyl, cycloalkyl or heterocycle containing oxygen, sulfur or NR3; Y represents oxygen, hydroxy, alkyl, alkoxy and NHR5, or form = O, or = N-OR4; R3 represents hydrogen, alkyl or cycloalkyl; R4 represents hydrogen, alkyl, cycloalkyl or aryl; R5 represents hydrogen, alkyl, cycloalkyl or -COOtbu; R6 represents hydrogen, halogen, hydroxyl, alkyl, alkoxy or NHR3; These products are in all isomeric forms and their salts, as medicines. |