abstract |
The present invention provides non-steroidal Formula 1 compounds that are selective modulators (i.e. agonists and antagonists) of a steroid receptor, specifically the glucocorticoid receptor. The present invention also provides pharmaceutical compositions containing these compounds, and methods for using these compounds in order to treat animals that require therapy with glucocorticoid receptor agonists or antagonists. Glucocorticoid receptor modulators are useful for treating diseases such as obesity, diabetes, inflammation and other diseases such as those described above. The present invention also provides intermediate products and processes for preparing these compounds. (see formula). |