| abstract |
Pharmaceutical compositions incorporate compounds that affect the production and / or secretion of cytokines; said compounds include aryl substituted olefin amine compounds, pyridyloxyalkylamines and phenoxyalkyl amine and aryl substituted amine compounds, such as 3-aminophenyl amine compounds; said pharmaceutical compositions can treat a wide variety of conditions, diseases and disorders, and in particular those related to production dysfunction and / or cytokine secretion; Of particular interest are pharmaceutical compositions useful for preventing and treating conditions and diseases and disorders related to high levels of undesirable production and / or secretion of cytokines; Such pharmaceutical compositions are useful for treating the effects of inflammatory bowel disease, inflammation, arthritis, cachexia in neoplasic or AIDS-related diseases, and autoimmune diseases. |