| abstract |
The present invention describes compounds of formula (I): (see formula) wherein: X represents a heterocycle attached to the rest of the molecule by a nitrogen atom of the heterocycle, or a group -NR2R3 wherein R2 represents a hydrogen atom or an alkyl group, and R3 represents an aryl group, a 1,3-dihydro-2H-benzimidazolyl-2-one group, or an alkyl group substituted by a heterocycle, n represents zero or 1, R1 represents a hydrogen atom or an alkyl group, Ra represents a single bond or an alkylene chain, A represents a nitrogen atom or a CH group, E represents a nitrogen atom or a CRe group, where Re is as defined in the description, Rb represents a single bond or an alkylene chain as defined in the description, W represents an aryl group or a heteroaryl group, its optical isomers and addition salts thereof with a pharmaceutically acceptable acid. Medicines. |