| abstract |
Compounds and pharmaceutical compositions active against the hepatitis B virus are provided, as is a method for the treatment of hepatitis B virus infection in humans and other host animals, which comprises administering an effective amount of a ?? - L- (2 ?? - or 3 ?? - azido) -2 ??, 3 ?? - dideoxy-5-fluorocytosine of the formula (I) in which R is H, acyl, monophosphate, diphosphate or triphosphate, or a stabilized phosphate derivative (to form a stabilized nucleotide based prodrug) and R ?? is H, acyl or alkyl. |