Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_96803e6feb7779def6d5e4a295ef62b5 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S424-81 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0636 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-17 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0783 |
filingDate |
1999-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7afefd45902ab4b89db5e4054ecd8f64 |
publicationDate |
2002-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
MX-PA01001144-A |
titleOfInvention |
INHIBITION OF GRAFT DISEASE AGAINST GUEST. |
abstract |
The development of graft versus host disease in a mammalian patient undergoing cell transplant therapy for the treatment of a bone marrow-mediated disease is prevented or relieved by submitting at least the T cells of the allogeneic cell transplant composition, extracorporeally, to an oxidizing stress, in appropriate dose amounts, such as boiling a gaseous mixture of ozone and oxygen through a suspension of the T cells. The process may also include irradiation of the cells with UV light, simultaneously with the Application of oxidative stress. Oxidizing stress induces reduced production of inflammatory cytokine and a reduced proliferative response in T cells. |
priorityDate |
1998-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |