| abstract |
The invention relates to new 3,3-diphenylpropylamines derivatives, methods for their preparation pharmaceutical compositions containing the new compounds and the use of the compounds to prepare drugs. More particularly, the invention relates to new prodrugs of antimuscarinic agents with superior pharmacokinetic properties compared to existing drugs such as oxybutynin and tolterodine, methods for their preparation, pharmaceutical compositions containing them, a method for using these compounds and compositions. for the treatment of incontinenceurinary, gastrointestinal hyperactivity (irritable bowel syndrome) and other contractile conditions of the smooth muscle. |