| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_96f584021b3ff9f2f3daa465aa0f2c35 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-61
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-1133
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K19-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-61
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-113 |
| filingDate |
1998-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab3721ad541732e1562fdfffbdd1a5d4 |
| publicationDate |
2004-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
MX-PA00009564-A |
| titleOfInvention |
CHEMICAL PROTEIN CONTAINING A SIMILAR SEQUENCE TO THE INTRAMOLECULAR CAPERONE AND ITS APPLICATION TO INSULIN PRODUCTION. |
| abstract |
The present invention relates to a chimeric protein that contains a sequence similar to the intramolecular caperone (BMI) linked to the target protein, preferably an insulin precursor. The present invention also relates to a process for obtaining a chimeric protein containing correctly folded insulin precursor, which comprises; inter alia, contacting an incorrectly folded chimeric protein containing a sequence similar to BMI linked to an insulin precursor with at least one chaotropic auxiliary agent. The present invention also relates to an assay to select an amino acid sequence for its ability to improve the folding of an insulin precursor using a chimeric protein that contains a BMI-like sequence linked to an insulin precursor. |
| priorityDate |
1998-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |