| abstract |
A class of substituted 1,2,4-triazolo [4,3-b] pyridazine derivatives, which possess a fluoro substituted phenyl ring at position 3 and a heteroaryl methoxy portion at position 6, are selective ligands for receptors GABAA, in particular that they have high affinity for the alpha-2 and / or alpha-3 sub unit thereof, and are in accordance with this of benefit in the treatment and / or prevention of central nervous system disorders, including anxiety and seizures |