http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MX-PA00000280-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a2901e694724c2a759f619944cb7d2a4 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D241-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D241-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4965 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4965 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4402 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4406 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4418 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 |
filingDate | 1998-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_657e0e9b33c5a1d39ac857e278a064ce |
publicationDate | 2002-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | MX-PA00000280-A |
titleOfInvention | DERIVATIVES OF PIRAZINA, ITS PREPARATION AND THE MEDICINES CONTAINING THEM. |
abstract | The invention relates to pyrazine derivatives of the formula (I) in which: R represents a nitrogen atom, R1 represents a radical ûCO-NR5R6, -CO- N (CH (CH2OH) 2) 2, -CO-N (CH2OH) 2, -CO-N- (CH2-CH (CH2OH) 2), -CO- N (CH2- (CHOH), - CH2OH) 2, CH2-O-R6, -NR6-CO-R6, - OH2-NR2R6, -CH2-N (CH2OH) 2, -CH2-N (CH2- (CHOH) 2-CH2OH; -CH2-N (CH (CH2OH) 2) 2, -CH2-N (CH2-CH (CH2OH2 ) 2 and one of its substituents; R2 or R4 represent a hydrogen atom and the other is identical to R1, and R2 represents a hydrogen atom, or R represents a radical CH, R1 and R4 are identical and each represent a radical ûCO-NNR5R6, -CO- N (CH (CH2OH) 2) 2, -CO-N (CH2OH) 2, -CO-N (CH2- CH (CH2OH) 2), -CO- N (CH2- (CHOH) 6-CH2OH) 2, -CH2-O-R6, -NR5-CO-R6, -CH2- NR5R6, -CH-N (CH2OH) 2, -CH2-N (CH2- (CHOH) and -CH2OH) 2, -CH2- N (CH (CH2OH) 2) 2, - CH2-N (CH2-CH (CH2OH) 2) 2; and R5 and r6 represent a hydrogen atom, or R1 and R2 are identical and each represent a radical ûCO-NR5R6, -CO- N (CH (CH2OH) 2) 2, -CO-N (CH2OH) 2, -CO-N (CH2-CH (CH2OH) 2) 2, -CO- N (CH2- (C HOH) 6-CH2OH) 2, -CH2-O-R6, -NR6-CO-R6, -CH2-NR5R6, -CH2-N (CH2OH) 2, -CH2- N (CH2- (CHOH) and -CH2OH) 2, -CH2- N (CH (CH2OH) 2) 2, -CH2-N (CH2-CH (CH2OH) 2) 2 and R5 and R4 represent a hydrogen atom, or R2 and R3 are identical and each represent a radical ûCO-NR5R6, -CO- N (CH (CH2OH) 2) 2, -CO- N (CH2OH) 2, -CO-N (CH2-CH (CH2-OH) 2) 2), -CO- N ( CH2- (CHOH) 6-CH2OH) 2, -CH2-O- R6, -NR5-CO-R6, -CH2-NR5R6, - CH2-N (CH2OH), -CH2-N (CH2- (CHOH) and- CH2OH) 2, OH2- N (CH (CH2OH) 2) 2, -CH2N (CH2-CH (CH2OH) 2) 2 and R4 and R4 represent a hydrogen atom, its stereoisomers, its salts, the new derivatives of the formula (I) and its preparation. |
priorityDate | 1997-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 264.