| abstract |
Compounds are described which respond to the general formula (I), where R1 is an alkyl group of 1 to 4 carbon atoms or a cycloalkylmethyl group of 3 to 7 carbon atoms, X1 is a hydrogen or halogen atom or a group alkoxy of 1 to 4 carbon atoms or, OR1 and X1 together form a group of formula -OCH2O-, -O (CH2) 2-, -O (CH2) 3-, -O (CH2) 2O- or -O ( CH2) 3O, X2 represents a hydrogen atom or an amino group, X3 is a hydrogen or halogen atom and R2 is a hydrogen atom, an optionally substituted alkyl group of 1 to 6 carbon atoms, a phenyl-alkyl group from 1 to 4 carbon atoms which is optionally substituted on the phenyl ring, a phenyl-alkenyl group of 2 to 3 carbon atoms, a phenoxy-alkyl group of 2 to 4 carbon atoms, a cycloalkylmethyl group of 3 to 7 carbon atoms, a 2,3-dihydro-1H-inden-1-yl or 2,3-dihydro-1H-inden-2-yl group or a group of general formula - (CH2) nCO-Z, in the which n is a number from 1 to 6 and Z is a piperidi n-1-yl or un can be used to treat and prevent disorders in which 5-HT4 and / or H3 receptors are involved, particularly in the central nervous system, the gastrointestinal system, the lower urinary organs, or the cardiovascular system. |