http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MX-9802107-A

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Predicate Object
assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3e93d357c3fcb571238ff08afe6072cd
classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2123-00
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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0497
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
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filingDate 1998-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d731ed0ec3c718d69016f38d06810eaa
publicationDate 1998-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber MX-9802107-A
titleOfInvention RADIOACTIVE MARKED BIOTINE DERIVATIVES.
abstract The invention relates to a labeled biotin compound, wherein said biotin compound is represented by the general formula (I): where: n is 1 or 2, R is a chelating group for chelating a metal atom, and Sp it is a spacer group having at least 4 atoms that separate NH from R; and wherein said biotin compound is labeled with a metal atom selected from a) the group consisting of the radioactive isotopes 99mTc, 203Pb, 66Ga, 67Ga, 68Ga, 72As, 111In, 113mIN, 114mIN, 97Ru, 62Cu, 64Cu, 52Fe, 52mMn, 51Cr, 186Re, 188Re, 77As, 90Y, 67Cu, 169Er, 117mSn, 121Sn, 127Te, 142Pr, 143Pr, 198Au, 199Au, 149Tb, 161Tb, 109Pd, 165Dy, 149Pm, 151Pm, 153Sm, 157Gd, 166Ho, 172Tm, 169Yb, 177Lu, 105Rh and 111Ag or b) the group consisting of the paramagnetic metal atoms Cr, Mn, Fe, Co, Ni, Cu, Pr, Nd, Sm, Yb, Gd, Tb, Dy, Ho and Er ; said metal atom being attached to the biotin compound by means of said chelating group; The invention also relates to a pharmaceutical composition comprising the labeled biotin compound, to the use of said composition for diagnosis and therapy, and to equipment for preparing a radiopharmaceutical composition.
priorityDate 1995-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Predicate Subject
isDiscussedBy http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID458396881

Total number of triples: 27.