http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MX-9704774-A

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filingDate 1995-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86fc6cba815b2d91fa136dc5a63d57f2
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publicationDate 1997-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber MX-9704774-A
titleOfInvention DERIVATIVES OF 19-NOR-PROGESTERONE BRIDGED IN C2 14ALFA, 17ALFA.
abstract The invention relates to C2 14, 17 bridged steroids of the general formula 1, wherein R3 represents one oxygen atom, the hydroxyamino group or two hydrogen atoms; R6 represents either a hydrogen, fluorine, chlorine or bromine atom or a C1-C4 alkyl group in the alpha or beta position, R6 and R7 then represent hydrogen atoms; or alternatively, R6 represents a hydrogen, fluorine, chlorine or bromine atom or a C1-C4 alkyl group, R6 and R7 then represent a further common bond; R7 represents a C1-C4 alkyl group in the alpha or beta position; R6 and R6 'then represent hydrogen atoms or alternatively R6 and R7 together represent a hydrogen atom; or R6 and R6 'together represent an ethylene or methylene group and R7 represent a hydrogen atom; R9 and R10 each represent a hydrogen atom or a common bond; R11 and R12 each represent a hydrogen atom or a common bond; R13 represents a methyl or ethyl group; R15 represents a hydrogen atom or a C1-C3 alkyl group; R16 and R16 'independently of each other represent a hydrogen atom, a C1-C3 alkyl group or a C2-C4 alkenyl group or together represent a C1-C3 alkylidene group; R15 and R16 represent a common bond and R16 'represents a hydrogen atom or a C1-C3 alkyl group or alternatively R15 and R16 together represent a ring of the partial formula (i) shown, in which N = 1 and 2 and X represents a methylene group or an oxygen atom; and R16 'represents a hydrogen atom; R17ü represents a hydrogen atom or a C1-C3 alkyl group; R17² represents a hydrogen atom, a C1-C3 alkyl group or a C2-C4 alkenyl group; R17ü and R17² each represent a hydrogen atom or a common bond; R²ü represents a hydrogen atom or a C1-C3 alkyl group and R²ü represents a hydrogen atom, a C1-C3 alkyl group or a hydroxy group. The claimed compounds do not include 14, 17-ethane-19-norpregn-4-en 3,20-dione. The new compounds, unlike the one not claimed, show a high level of gestagenic activity even after peroral administration and are suitable for use in the production of drugs.
priorityDate 1994-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 41.