| abstract |
Phenyloxazolidinone compounds of Formula I, or the pharmaceutically acceptable salt thereof, characterized by a bicyclic thiazine, or oxazine substituent. The compounds are useful as antimicrobial agents, effective against a number of human and veterinary pathogens, including gram-positive aerobic bacteria, such as staphylococci, streptococci, and enterococci resistant to multiple drugs, as well as anaerobic organisms, such as Bacteroides spp. and Clostridia spp., and acid resistant organisms such as Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium spp. |