| abstract |
This invention provides a topical composition, in the form of an emulsion, comprising a compound of the class of FK506; a physiologically acceptable alkanediol, ether diol, or diether alcohol containing up to 8 carbon atoms as a solvent for the compound of class FK506; a fatty alcohol unsaturated in water. In another aspect, this invention provides a topical pharmaceutical composition comprising a suspension macrolide. In a traditional aspect, this invention provides the use of an unsaturated free alcohol to stabilize a macrolide in a pharmaceutical composition. |