Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_170f4c8b5df6a5bb879c0f4452a13e1d |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-8103 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-48 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-64 |
filingDate |
1995-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c2a26216804e25ee07b2caad984b68aa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6dcc0a7c8f5a9093bad199e2ce385db9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a222f8695e017970aa875fa4944ee015 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b9bd94fd66e13104399cc6f27f6bd65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d45f7611211cc2aecebc865d05274b6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7857aba04f61018cec71a2aa622143c4 |
publicationDate |
1998-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
MX-9702152-A |
titleOfInvention |
CLONING OF A MEMBRANE AMINOPEPTIDASE, INSULIN DEPENDENT, FROM GLUT-4 VESICLES. |
abstract |
An insulin dividing peptidase has been purified from GLUT-4 containing vesicles and cloned. Peptidase has a measured mass of approximately 165 kD, but is 110 kD in its glycosylated state. A mass of 117,239 Daltons has been predicted based on the predicted amino acid sequence of the cDNA in the figure (SEQ ID Nos: 15 and 16). Includes peptides having the amino acid sequences Phe-Ala-Ala-Thr-Gln-Phe-Glu-Pro-Leu-Ala-Ala (sec id NO: 1) and Ile-Leu-Gln-Asn-Gln-Ile-Gln -Gln-Gln-Thr-Arg-Thr-As p-Glu-Gly-Xaa-Pro-Xaa-Met (SEQ ID NO: 2) and binds to antibodies produced against the peptide identified as (SEQ ID NO: 1 ). Modulators and a method for treating insulin resistance syndrome, including diabetes, by administering such a modulator are also claimed. |
priorityDate |
1994-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |