| abstract |
A procedure for preparing an optically active trans-3-phenylglycidamida compound is described, which comprises subjecting a racemic trans-3-phenylglycidamide compound of formula (I): wherein ring A is substituted or unsubstituted benzene, and R1 is H or lower alkyl, for optical resolution using a microorganism having the ability to preferably hydrolyze a (2S, 3R) isomer or a (2R, 3S) isomer thereof, and a process for preparing a 1.5 derivative optically active benzothiazepine from the optically active trans-3-phenylglycidamide compound thus obtained. |