| abstract |
The invention relates to compounds having formula (I), pharmaceutically acceptable addition salts, and stereochemically isomeric forms thereof, wherein Y is CH or N; R1, R2 and R3 are each independently hydrogen or C1-4alkyl; R4 and R5 are each independently hydrogen, halogen, C1-4alkyl, C1-4alkyloxy, hydroxy, trifluoromethyl, trifluoromethyloxy or difluoromethyloxy, R6 is hydrogen; or R6 is phenyl optionally substituted with halogen; pyridinyl; furanyl; thienyl, 3-chloro-benzo [b] thien-2-yl; trifluoromethyl; C1-4alkyloxycarbonyl; dihalogenophenylcyclopropanil; C3-6cycloalkyl, adamantyl; C2-6 alkenyl optionally substituted with halogenophenyl; or C1-4alkyl optionally substituted with halogen, phenyl, halogenophenyl, dihalogenophenyl, phenyloxy, piperidinyl, pyrrolidinyl, piperazinyl, C1-4alkylperazinyl, C1-4alkylcarbonylpiperazinyl, C1-4alkyloxycarbonylpiperazinyl, phthalimino, di-C1-20 alkylamino or cycloalkylamino C3-6; is C = O or CHOH, and (1) is a radical of formula (a-1), (a-2), (a-3), (a-4, (a-5), (a-6) or (a-7); compositions comprising said compounds, procedure for the preparation thereof and the use of these compounds as a medicine. |