| abstract |
The invention relates to compounds having formula (I), pharmaceutically acceptable addition salts, and stereochemically isomeric forms thereof, wherein Y is CH or N; R1, R2 and R3 are each independently hydrogen or C1-4alkyl; R4 and R5 are each independently hydrogen, halogen, C1-4alkyl, C1-4alkyloxy, hydroxyl, trifluoromethyl, trifluoromethyloxy or difluoromethyloxy; R6 is C1-4alkyl; or phenyl optionally substituted with halogen, C1-4alkylcarbonylamino, C1-4alkyloxy, C1-4alkyl or nitro; Z is C = O or CHOH; and (1) is a radical of formula (a-1), (a-2), (a-3), (a-4), (a-5), (a-6), or (a-7 ); compositions comprising said compounds, procedures for the preparation thereof and the use of these compounds as a medicine. |