| abstract |
The invention provides a condensed pyrazole derivative of formula (I); (where A denotes CH or N, R0 and R3 denote the same or different, a hydrogen atom or a lower alkyl group; R1 and R2, are the same or different, and are a hydrogen atom, a lower alkyl group, a lower alkoxy group, an alkylthio group, a nitro group, or a halogen atom, m denotes 1 or 2, and n denotes 1, 2, or 3 provided that, when n is 2, two R 2 can join together to form a lower alkylenedioxy group) or its pharmaceutically acceptable salt. This derivative or its salt is excellent in the effect of inhibiting the expression of androgen action, therefore it is excellent in the therapeutic effect of benign prostatic hypertrophy, prostatic carcinoma, etc., and has a long duration of activity and its high absorption. oral. |