| abstract |
A topical preparation containing cyclosporin as an active ingredient, containing (a) cyclosporin is described; (b) an organic solvent to dissolve said cyclosporin; (c) an ester of a fatty acid with a monovalent alcohol having a total number of carbon atoms of 8 or more and / or an alkanolamine, each being in a liquid state at 25 ° C; (d) an oily substance in solid state at 25 ° C; and (e) a surfactant; wherein said cyclosporin is in a ratio ranging from about 0.1 to 10 by weight and said ester and / or said alkanolamine is in a ratio ranging from about 1 to 15 by weight. Topical preparations are active against atopic dermatitis, psoriasis, allergic contact dermatitis. |