abstract |
The present invention relates to compounds of formula I: (see Formula) in which: Y is C-R1 ', R1' is hydrogen or halogen, R1 is hydrogen or halogen, R2 is hydrogen, lower alkyl or phenyl, R4 is hydrogen or lower alkyl, or R2 and R4 can form together with the corresponding atoms, to which they are attached, the following rings: (see Formulas) R5 is hydrogen or lower alkyl, and in the case that R2 and R4 form a ring as indicated above, R5 is hydrogen, or R4 and R5 can form, together with the C atom to which they are attached, a heterocycloalkyl ring, R3 is phenyl or pyridinyl, in which the N atom in the Pyridinyl group may be in different positions, or to a pharmaceutically acceptable salt or acid addition salt, to a racemic mixture or to its corresponding enantiomer and / or optical isomer and / or stereoisomer thereof. The compounds can be used for the treatment of Parkinson's disease, anxiety, emesis, obsessive-compulsive disorder, autism, neuroprotection, cancer, depression, and type 2 diabetes. |