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filingDate 2012-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53f800f4e3d6f36ca66fc7778e7596c8
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publicationDate 2019-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber MX-363561-B
titleOfInvention NASAL GELS OF CONTROLLED RELEASE OF TESTOSTERONE, METHODS AND PRE-LOADED MULTIDOSIS APPLICATOR SYSTEMS FOR PERNASAL ADMINISTRATION.
abstract The present invention relates to intranasal testosterone gels for the controlled release of testosterone in the systemic circulation of men and women to provide constant effective blood levels of testosterone, without inducing sudden unwanted peaks of testosterone in blood levels, after pernasal administration. . The intranasal testosterone gels of the present invention are safe, convenient to use, well tolerated, stable and easy to make and reproducible on a large scale. In addition, since it is believed that the supra-normal and sub-normal blood levels of testosterone are essentially kept to a minimum or avoided and it is believed that serum testosterone levels remain essentially constant over the life of the dose, i.e. , the intranasal testosterone gels of the present invention reproduce or restore blood testosterone levels to normal physiological daily rhythmic testosterone levels, the new intranasal testosterone gels of the present invention are especially suitable for supplemental or testosterone replacement therapy and effective for the treatment of men diagnosed with, for example, testosterone deficiency in men, such as low sexual libido, low sex drive, low sexual activity, low fertility, low spermatogenesis, aspermatogenesis, depression and / or hypogonadism, and women who were diagnosed, for example, feme sexual dysfunction Nina, such as low sexual libido, low sex drive, low sexual activity, low tonsil reactivity, low sexual stimulation, hypoactive sexual desire disease ("HSDD"), female sex drive disorder and / or anorgasmia. The present invention also relates to pre-loaded methods and systems of airless, multi-dose applicators for pernasal administration of nasal testosterone gels of the present invention.
priorityDate 2011-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

Incoming Links

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Total number of triples: 34.