| abstract |
The present invention relates to compounds of Formula (I), and pharmaceutically acceptable salts thereof, as Mpges-1 inhibitors. These compounds are inhibitors of microsomal prostaglandin synthase-1 enzyme (mPGES-1) and are therefore useful in the treatment of pain and / or inflammation from a variety of diseases or conditions, such as asthma, osteoarthritis, arthritis rheumatoid, acute or chronic pain and neurodegenerative diseases. |