| abstract |
The present invention relates to a method for simultaneously producing highly concentrated L-amino acids and riboflavin, and to a microorganism to simultaneously produce L-amino acids and riboflavin. More particularly, the present invention relates to a mutated un-microorganism to simultaneously produce L-lysine or L-threonine and riboflavin, wherein the microorganism is modified by improving the activity of a family of enzymes expressed by a rib operon that it contains a family of riboflavin biosynthesis genes in Corynebacterium, sp. capable of producing L-lysine or Ltreonine. Also, the present invention relates to a method for the simultaneous production of L-lysine, or L-threonine and riboflavin using the mutated microorganism, and refers to a granular preparation or preparation of foods and food additives containing L-lysine or L-threonine and riboflavin produced from a culture medium of the mutated microorganism. The microorganism characterized in that the microorganism Corynebacterium sp. It is selected from the group consisting of Corynebacterium glutamicum, Corynebacterium ammoniagenes, Corynebacterium thermoaminogenes, Brevibacterium flavum and Brevebacterium lactofermentum. |