| abstract |
The present invention relates to compounds for oral administration and treatment methods using VSP vehicle, such as the variable surface proteins (VSP) of Giardia sp., To administer therapeutic agents. VSP drug vehicles can be combined with bioactive peptides, eg, insulin, glucagon or hGH, and can be administered orally or mucosally. VSP vehicles are resistant to acidic pHs and proteolytic degradation and protect therapeutic agents from degradation in the intestinal tract. |