http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MX-347498-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_def263865fcae9da9c3b64eab42bc0d8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C229-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C229-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C229-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-08 |
| filingDate | 2012-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d23292615ae2008488502aa541d93ea7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98bd85bf7af34c8df7b7e00d2662d5b9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_837cc276844d61fac5e8a3a768730810 |
| publicationDate | 2017-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | MX-347498-B |
| titleOfInvention | HYDRAATED N-FULERENE AMINO ACIDS, METHOD TO PRODUCE THE SAME, AND PHARMACEUTICAL COMPOSITIONS BASED ON THE SAME. |
| abstract | The invention relates to the pharmaceutical industry and to medicine, specifically to new hydrated C60 amino acid derivatives of general formula C60 (H) 3 {NH (CH2) nCOOH} 3 xH2O, wherein C60 is fulerene, n = 5, 6, 7, x = 8-10, and also to a method for producing said derivatives, and to the production of pharmaceutical compositions based thereon. Hydrated fulerene amino acids are formed in the interaction of fulerene with a 15-fold molar excess of anhydrous potassium salts of amino acids in an organic aromatic solvent medium with a slow addition to the suspension resulting from a phase transfer catalyst and with mixing and heating at a temperature not exceeding 60 ° C until the solution is completely discolored and a solid residue is formed, after which it is separated, and then 0.8 M aqueous solutions of potassium salts of fulerene amino acid derivatives are treated with an organic or mineral acid solution, followed by centrifugation, washing, and drying of the residue. A pharmaceutical composition that exhibits activity against the herpes virus, influenza viruses of various origin and HIV, and also anti-tumor and anti-psoriatic activity, which comprises, as active substance, an effective amount of hydrated N-fulerene amino acids. |
| priorityDate | 2011-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.