http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MX-342537-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4d3f1bfec8ac94cca9554e3c17db5c6d |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J75-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-0018 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-565 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-0059 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J75-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-565 |
| filingDate | 2012-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a46f594b1e0239d5ea128f9270b0e2be |
| publicationDate | 2016-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | MX-342537-B |
| titleOfInvention | PROCESS FOR THE PRODUCTION OF ESTETROL INTERMEDIARIES. |
| abstract | The present invention relates to a process for the preparation of a compound of formula (I), comprising the steps of: (a) reacting a compound of formula (II), with a silylating agent or acylating agent to produce a compound of formula (III), wherein P1 is a protecting group that is selected from R2Si-R3R4 or R1CO-, R1 is a group that is selected from alkyl of 1 to 6 carbon atoms or cycloalkyl of 3 to 6 carbon atoms, each group is optionally substituted by one or more substituents that are independently selected from fluoro or alkyl of 1 to 4 carbon atoms; R2, R3 and R4 are each independently a group that is selected from alkyl of 1 to 6 carbon atoms or phenyl, each group is optionally substituted by one or more substituents that are independently selected from fluoro or alkyl of 1 to 4 atoms of carbon; b) halogenation or sulfinylation of the compound of formula (III) to produce a compound of formula (IV); wherein X is halo, or -O-SO-R5 and R5 is a group selected from aryl of 6 to 10 carbon atoms or heteroaryl, each group is optionally substituted by one or more substituents that are independently selected from chlorine or alkyl of 1 to 4 carbon atoms; c) dehalogenation or desulfinylation of the compound of formula (IV) to produce the compound of formula (V); and d) reacting the compound of formula (V) with a reducing agent to produce a compound of formula (I). |
| priorityDate | 2011-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.