Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_634f9eaf572cc875324ed64fa6f7bc77 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-05 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J27-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D451-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0438 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-04 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C19-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B59-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D451-02 |
filingDate |
2010-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db75f3302fbae80b9be3b85dfa0abe6b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cdac88769e13f6965d4ca4b52259a588 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd4f867f0f06c991e2fc86e847192c4a |
publicationDate |
2016-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
MX-339670-B |
titleOfInvention |
PREPARATION OF N-MONOFLUOROALQUI TROPANOS. |
abstract |
The present invention relates to an improved synthesis of N-monofluoroalkyl tropanes using fluoroalkyl iodides or fluoroalkyl sulphonate esters. The present invention also provides the use of said method to prepare FP-CIT non-radioactive tropane intermediates, and their subsequent conversion to 123L-labeled radiopharmaceutical DaTSCANTM (123l-yoflupane). The use of fluroalkyl iodides or fluoroalkyl sulphonate esters in the alkylation method of the present invention is also provided. |
priorityDate |
2009-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |