abstract |
(S) -trans- {4 - [({2 - [({1- [3,5-bis (trifluoromethyl) phenyl] ethyl} {5- [2- (methylsulfonyl) ethoxy] pyrimidin-2-yl) } amino) methyl] -4- (tr ifluoromethyl) phenyl} (ethyl) amino) methyl] cyclohexyl} acetic optically pure, or a salt thereof or a solvate thereof, which has actions to reduce the amount of PCSK9 protein and increase the amount of the LDL receptor. |