http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MX-3341-E
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69c91bbf0395db010b4806f50d808c4e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J13-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J71-001 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J31-006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J41-0005 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-568 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J71-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J41-00 |
| filingDate | 1976-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b396a8aabc1b547165a2f96fcd62ed9a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9285893b481b80094c16420fe858a21e |
| publicationDate | 1980-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | MX-3341-E |
| titleOfInvention | PROCEDURE FOR THE PREPARATION OF EPOXY-ANDROSTANS |
| abstract | The present invention relates to a process for the preparation of epoxy-androstanes, of the formula I: (SEE FIGURE) in which X is halogen, Z1 and Z2 both represent hydrogen, or Z1 is hydroxy and Z2 is chlorine, or Together Z1 and Z2 denote an epoxy group, which comprises reacting a compound of formula V: (SEE FIGURE) in which R1 and R2 both represent hydrogen or hydroxy, with hydrazine, in an organic solvent at an elevated temperature , preferably at the boiling point of the reaction mixture, treat the compound obtained of formula IV (see figure) where R1 and R2 have the above meanings, with an N-halo-succinimide at a temperature of minus 30 to + 20 ° C, to provide the corresponding compound of formula III: (see figure) where X, R1 and R2 have the above definitions, and then react a compound of formula III, where R1 and R2 are both hydrogen, with a peracid organic at a temperature between 20 and 30 ° C , to provide a product of formula I, wherein Z1 and Z2 are both hydrogen. |
| priorityDate | 1975-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.