http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MX-3103-E
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e5edd48190cba3fa70dd3975efd9831 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C215-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-137 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-135 |
| filingDate | 1973-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf18aed57619c7252babb8af7c440f9d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a4d1697b38d804b51d7e3e4f92b5104 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bdde8a94a5ae103d7d11b4dc53a9ae95 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d7762e1ec1052f9e7e13d2074cb484d |
| publicationDate | 1980-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | MX-3103-E |
| titleOfInvention | PROCEDURE TO PREPARE BENCIL AMINAS |
| abstract | The present invention relates to the preparation of benzylamines of the general formula I: (SEE FIGURE) in which Hal signifies a chlorine or bromine atom, R1 signifies a hydrogen, chlorine or bromine atom, R2 signifies the morpholinocarbonylmethyl radical, a branched alcohol radical with 3 to 5 carbon atoms, optionally substituted with 1 to 3 hydroxyl groups, or a group of the formula: (SEE FIGURE) where R3 means a hydrogen atom, a hydroxy group or an alcohol group with 1 to 4 carbon atoms, n means the numbers 0, 1 or 2 and the two radicals A and B mean hydrogen atoms or together the group (SEE FIGURE) where R5 represents a hydrogen atom or a lower alcohol radical with 1 or 2 carbon atoms and m signifies the numbers 1 or 2, R4 signifies a straight or branched chain alcohol radical with 1 to 4 carbon atoms, an alkenyl radical with 2 to 4 carbon atoms, a cycloalkyl radical with 3 or 4 carbon atoms or also an atom of hydrogen, in case R3 does not represent any hydrogen atom, or R2 represents a branched alcohol radical with 3 to 5 carbon atoms, possibly substituted with 1 to 3 hydroxyl groups, and 1 signify the numbers 1 or 2, being a halogen atom in position 2, as well as its acid addition salts physiologically compatible with organic or inorganic acids, characterized in that a phenol of the general formula II is reacted (SEE FIGURE), in which R1, Hal are as initially defined , one of the radicals Hal being in position 2 of the compound of the general formula VIII, with formaldehyde or paraformaldehyde and with an amine of the general formula III, (SEE FIGURE) in which R2 and R4 are as initially defined, in a solvent and at a temperature from 0 to 100 ° C, and a compound of the general formula I, obtained according to the procedure, is subsequently transformed, if desired, into its physiologically compatible salts with ac organic or inorganic gone. |
| priorityDate | 1972-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 35.