| abstract |
Broadly, this description relates to compositions comprising a crosslinked polymer with cation bonds comprising monomers containing carboxylic acid groups and pKa-lowering groups including electron-withdrawing substituents such as halide atoms (for example, fluorine ) and a base, wherein the polymer optionally contains less than about 20,000 ppm cations other than hydrogen and wherein the base is present in an amount sufficient to provide from about 0.2 equivalents to about 0 0.95 equivalents of base per equivalent of carboxylic acid groups in the polymer. The present description also refers to methods of preparing such compositions and methods of using them to treat various diseases or disorders. |