http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MX-2020006214-A

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filingDate 2018-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c8f3fc42acd9e6491b7f2893ee47865
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publicationDate 2020-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber MX-2020006214-A
titleOfInvention COMPOSITION OF DRY IMPLANT AND INJECTABLE AQUEOUS IMPLANT FORMULATION.
abstract The invention relates to: - a dry implant composition consisting essentially of a mixture of nanocrystalline hydroxyapatite particles derived from natural bone having a size of 50 to 200 µm and fragments of naturally interlocked fibrous collagenous material passing through a 0.5 mm sieve, with which the w/w ratio of hydroxyapatite to collagen is from 1.8 to 4.5; - the use of that dry implant composition for the preparation of an injectable aqueous implant formulation for use in the regeneration of oral tissue that is extrudable through a conical system and an 18 gauge cannula (0.838 mm internal diameter) of 25.4 mm long; - an injectable aqueous implant formulation for use in oral tissue regeneration, wherein the injectable aqueous implant formulation can be obtained by rehydrating and homogeneously mixing 25-45% w/w of the above dry implant composition with sterile water o a sterile isotonic saline solution, which can be extruded through a conical system and a 25.4 mm long 18 gauge (0.838 mm internal diameter) cannula with a force not exceeding 60 N;- a procedure for the preparation of the above injectable aqueous implant formulation comprising rehydrating and homogeneously mixing 25-45% w/w of a dry implant composition as defined above in sterile water or a sterile isotonic saline solution; - a kit for the preparation of the above injectable aqueous implant formulation for use in oral tissue regeneration, comprising: - a syringe equipped with a mixing device containing a dry implant composition as defined above, a conical system and an 18-gauge cannula (0.838 mm internal diameter) 25.4 mm long; - a container filled with an appropriate amount of sterile water or a sterile isotonic solution.
priorityDate 2017-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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