| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cd5537af900106df1a2e4d63470098e3 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-10 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-10 |
| filingDate |
2015-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f4bed309e6f08b1ad4c4266224125cb |
| publicationDate |
2021-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
MX-2020003758-A |
| titleOfInvention |
METHODS FOR SEPARATING DIASTEREOISOMERS OF GEMCITABINE-PHOSPHATE. |
| abstract |
This application relates to a method for separating the phosphate diastereoisomers of gemcitabine-[phenyl-benzoxy-L-anani nil)]-phosphate (NUC-1031) using crystallization; in particular, crystallization from isopropyl alcohol provides gemcitabine-[phenyl-benzoxy-L-alaninyl)]-(S)-phosphate in highly diastereomerically pure form; This application is also related to a crystalline form of gemcitabine-[phenyl-benz oxy-L-alaninyl)]-(S)-phosphate. |
| priorityDate |
2014-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |