abstract |
The present invention belongs to the field of medicinal chemistry. Specifically described is a class of URAT1 inhibitors for increasing uric acid excretion, which are compounds represented by the structure of formula (I) or pharmaceutically acceptable salts thereof. Experiments show that the compounds provided by the present invention have a very good inhibitory effect on uric acid transport by hURAT1 in HEK293-transfected cells, and that these compounds have a good applicability in the treatment of hyperuricemia or gout. |