| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e1b6537673dd1a8c3c317c95e779a8fa |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y101-01001
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y207-08007
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y203-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y602-01001 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-93
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y101-01001
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y207-08007
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C39-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y203-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1288
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y205-01041
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1085
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C65-05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y602-01001
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0006
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y205-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1029 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C39-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C65-05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-81
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-52 |
| filingDate |
2018-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a28b718c93bd2fd128b4b8e34b08cec0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e85b14b1c69f1bcc284a88f169b8c9b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42177a9425fa37f7391d72e183bd408c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_39bcbdeb234a11980630e535eacbc611 |
| publicationDate |
2020-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
MX-2019009708-A |
| titleOfInvention |
METHOD AND CELL LINE FOR THE PRODUCTION OF PHYTOCANNABINOIDS AND ANALOGS OF PHYTOCANNABINOIDS IN YEAST. |
| abstract |
A method and cell line for producing phytocannabinoids and phytocannabinoid analogs in yeast. The method applies, and the cell line includes, a yeast cell transformed with a CDS polyketide synthase and a cytosolic CDS prenyltransferase. The enzyme polyketide synthase catalyzes the synthesis of olivetol or methyl-olivetol, and may include Cannabis sativa olivetolic acid synthase or Dictyostelium discoideumi polyketide synthase ("DiPKS"). The yeast cell can be modified to include a phosphopantethienyl transferase for increased DiPKS activity. The yeast cell can be modified to mitigate the catabolism of mitochondrial acetaldehyde to increase the malonyl-CoA available for olivetol or methyl-olivetol synthesis. The enzyme phenyltransferase catalyzes the synthesis of cannabigerol or a cannabigerol analog, and may include a cytosal enzyme phenyltransferase aßßa from Streptomyces sp CL190. The yeast cell can be modified to mitigate geranyl pyrophosphate depletion to increase geranyl pyrophosphate available for prenylation. |
| priorityDate |
2017-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |